rad 51 (Santa Cruz Biotechnology)

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Santa Cruz Biotechnology rad 51
Rad 51, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1223 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rad+51/Rad51+Antibody/pmc11729229-46-34-37
Average 96 stars, based on 1223 article reviews

rad 51 - by Bioz Stars, 2026-10

96/100 stars

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Cell Analysis:

Article Title: PARP inhibitor olaparib sensitizes esophageal carcinoma cells to fractionated proton irradiation
Article Snippet: .. First, antibodies for Rad 51 (sc-8349), BRCA1 (sc-642), BRCA2 (sc-28235) and 53BP1 (sc-22760) (Santa Cruz Biotechnology, CA, USA) were used and the foci in each cell were counted using HCS Studio 2.0 Cell Analysis Client Software, then the mean number of foci per nucleus was calculated. ..

Software:

Immunofluorescence:

Article Title: Ferulic acid in combination with PARP inhibitor sensitizes breast cancer cells as chemotherapeutic strategy.
Article Snippet: Homologous-recombination (HR)-dependent repair defective cells are hypersensitive to poly (ADPribose) polymerase (PARP) inhibitors.. Combinations of defective HR pathway and PARP inhibitors have been an effective chemotherapeutic modality.. We previously showed that knockdown of the WD40repeat containing protein, Uaf1, causes an HR repair defect in mouse embryo fibroblast cells and therefore, increases sensitivity to PARP inhibitor, ABT-888.

Incubation:

Article Title: DRG2 levels in prostate cancer cell lines predict response to PARP inhibitor during docetaxel treatment
Article Snippet: Membranes were blocked with 5% bovine serum albumin (BSA; bioWORLD) in Tris-buffered saline with Tween ® 20 (TBST) for 1 hour at room temperature. .. Membranes were subsequently washed with TBST and incubated overnight at 4°C with the following primary antibodies: DRG2 (14743-1-AP; Proteintech), caspase-3 (#9662; Cell Signaling Technology [CST]), p53 (#2524; CST), cdc2 (#9116; CST), PARP (#9542; CST), Rad 51 (sc-377467; Santa Cruz Biotechnology), and β-actin (sc-47778; Sigma-Aldrich Inc.) diluted in 5% BSA/TBST. .. The membranes were again washed with TBST and then incubated for 1 hour in a TBST containing the 2,000-fold diluted secondary antibody anti-mouse or anti-rabbit IgG HRP conjugate (Bethyl Laboratories).

Article Title: DRG2 levels in prostate cancer cell lines predict response to PARP inhibitor
Article Snippet: Membranes were blocked with 5% bovine serum albumin (BSA; bioWORLD, Dublin, OH, USA) in tris-buffered saline with tween®20 (TBST) for 1 h at room temperature. .. Membranes were subsequently washed with TBST and incubated overnight at 4°C with the following primary antibodies: DRG2 (14743-1-AP; Proteintech, Rosemont, IL, USA), caspase-3 (#9662; Cell Signaling Technology [CST], Danvers, MA, USA), p53 (#2524; CST), cdc2 (#9116; CST), PARP (#9542; CST), Rad 51 (sc-377467; Santa Cruz Biotechnology, Santa Cruz, CA, USA), and β-actin (sc-47778; SigmaAldrich Inc., MO, USA) diluted in 5% BSA/TBST. .. The membranes were again washed with TBST and then Page 4/16 incubated for 1 h in a 2,000-fold diluted TBST containing the secondary antibody anti-mouse or antirabbit IgG HRP conjugate (Bethyl Laboratories, Montgomery, TX, USA).

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